INGREDIENTS
Liver Support
Glutathione: 1000mg
Liver Support Ingredients
What It Is: Glutathione is often called the body’s “master antioxidant” and is naturally produced in the liver. It consists of three amino acids: cysteine, glutamic acid, and glycine.
What It Does: Glutathione plays a critical role in liver detoxification and antioxidant defense throughout the body. This supplement helps maintain glutathione levels that may become depleted. Athletes using PEDs may particularly benefit from glutathione’s ability to help neutralize free radicals and support the liver’s natural detoxification processes.
N-Acetyl Cysteine (NAC) 1000mg
Liver Support Ingredients
What It Is: NAC is a derivative of the amino acid L-cysteine and serves as a direct precursor to glutathione, enhancing the body’s antioxidant capabilities.
For Athletes: NAC at 1000mg provides robust support for the body’s glutathione production. It may help athletes maintain their antioxidant defense systems, especially in the liver where metabolic processing occurs.
Why We Chose These Ingredients:
We used ingredients with proven ability to lower ALT/AST levels and enhance liver function under extreme stress. Research doesn’t lie – the study on Glutathione we reference states: “ALT levels significantly decreased following treatment with glutathione for 4 months. In addition, triglycerides, non-esterified fatty acids, and ferritin levels also decreased with glutathione treatment.”
We paired Glutathione with NAC not just as a precursor, but because NAC has established clinical use in treating DILI (Drug Induced Liver Injury). The science is clear: “Apparently, enhancing intracellular antioxidative systems remains a feasible strategy to counteract oxidative stress to alleviate cellular damage.” When you’re pushing boundaries, your liver needs this level of protection.
NAC: Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects – PMC
Why We Chose These Ingredients
We used ingredients with proven ability to lower ALT/AST levels and enhance liver function under extreme stress. Research doesn’t lie – the study on Glutathione we reference states: “ALT levels significantly decreased following treatment with glutathione for 4 months. In addition, triglycerides, non-esterified fatty acids, and ferritin levels also decreased with glutathione treatment.”
We paired Glutathione with NAC not just as a precursor, but because NAC has established clinical use in treating DILI (Drug Induced Liver Injury). The science is clear: “Apparently, enhancing intracellular antioxidative systems remains a feasible strategy to counteract oxidative stress to alleviate cellular damage.” When you’re pushing boundaries, your liver needs this level of protection.
NAC: Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects – PMC
Kidney Support
Astragalus Root Powder 3000mg
Kidney support Ingredients
What It Is: Astragalus is an herb that has been used in traditional Chinese medicine for centuries, known for its adaptive and immune-supporting properties.
For Athletes: Astragalus provides significant kidney support by helping maintain normal fluid balance and supporting the body’s natural filtration processes. This substantial amount may help athletes maintain kidney function during periods of intense training, supporting healthy creatinine clearance and urine output. Additionally, astragalus may help support a healthy immune system and normal inflammatory response, which is crucial for athletes maintaining rigorous training schedules.
Why We Chose This Ingredient: Beyond its benefits for healthy athletes, Astragalus delivers remarkable results for compromised kidney function. Clinical research on patients with CKD (Chronic Kidney Disease) demonstrates improved creatinine clearance, reduced proteinuria, and lower blood pressure. With evidence this compelling, we didn’t just include Astragalus – we dosed it at a massive 3g per serving. Enhanced athletes demand enhanced protection.
Astragalus:Astragalus (a traditional Chinese medicine) for treating chronic kidney disease – PMC (nih.gov)
Why We Chose These Ingredients
Why We Chose This Ingredient: Beyond its benefits for healthy athletes, Astragalus delivers remarkable results for compromised kidney function. Clinical research on patients with CKD (Chronic Kidney Disease) demonstrates improved creatinine clearance, reduced proteinuria, and lower blood pressure. With evidence this compelling, we didn’t just include Astragalus – we dosed it at a massive 3g per serving. Enhanced athletes demand enhanced protection.
Astragalus: Astragalus (a traditional Chinese medicine) for treating chronic kidney disease – PMC (nih.gov)
Cholesterol Support
Citrus Bergamot 1000mg
Cholesterol support
What It Is: Citrus bergamot is derived from the Citrus bergamia plant native to southern Italy, rich in unique flavonoids and polyphenolic compounds, including neo eriocitrin, naringin and neohesperidin among many others that have been of interest for their cardiovascular benefits
For Athletes: Citrus bergamot provides potent cardiovascular support by helping maintain healthy cholesterol and triglyceride levels already within normal ranges. Athletes concerned with cardiovascular health during training may benefit from bergamot’s ability to support healthy lipid profiles.
Why We Chose This Ingredient: The data on Bergamot is undeniable. In a study referenced in our analysis (Mollace 2018), researchers divided patients into three groups: one placebo and two receiving different Bergamot extracts. After just 30 days at doses between 1-1.2g daily, both treatment groups experienced dramatic improvements: “The bergamot polyphenolic fraction
decreased total cholesterol from 262 to 196, LDL cholesterol from 175 to 116, and triglycerides from 252 to 170.”
Results this significant made Bergamot non-negotiable for our formula. When you’re operating beyond natural limits, your lipid profile needs this level of support.
Citrus Bergamot: Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers – PMC (nih.gov)
Why We Chose These Ingredients
Why We Chose This Ingredient: The data on Bergamot is undeniable. In a study referenced in our analysis (Mollace 2018), researchers divided patients into three groups: one placebo and two receiving different Bergamot extracts. After just 30 days at doses between 1-1.2g daily, both treatment groups experienced dramatic improvements: “The bergamot polyphenolic fraction
decreased total cholesterol from 262 to 196, LDL cholesterol from 175 to 116, and triglycerides from 252 to 170.”
Results this significant made Bergamot non-negotiable for our formula. When you’re operating beyond natural limits, your lipid profile needs this level of support.
Citrus Bergamot: Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers – PMC (nih.gov)
Blood Pressure Support
Arjuna: 750mg
Blood Pressure Support
What It Is: Terminalia arjuna is derived from the bark of the Arjuna tree native to India, with a long history of use in Ayurvedic medicine for cardiovascular support.
For Athletes: Terminalia arjuna provides robust cardiac support for athletes concerned with maintaining heart health during intense training. It may help maintain normal cardiac output, healthy blood pressure already within normal ranges, and overall cardiovascular function. Athletes using performance enhancers may benefit from arjuna’s potential to support cardiac muscle integrity and normal heart rhythm.
Hawthorn Berry P.E. 5:1: 250mg
Blood Pressure Support
What It Is: Hawthorn berry extract comes from the Crataegus plant, concentrated at a 5:1 ratio to provide potent cardiovascular benefits.
For Athletes: Concentrated hawthorn berry extract (equivalent to 1250mg of whole berry) contains flavonoids that may help support healthy blood flow and cardiac efficiency. It may help maintain healthy blood pressure already within normal ranges and support overall cardiovascular health. The potent 5:1 extract helps athletes maintain normal heart function during periods of intense physical activity, supporting optimal oxygen delivery and normal vascular tone.
Nattokinase: 600mg
Blood Pressure Support
What It Is: Nattokinase is an enzyme extracted from natto (fermented soybeans) that supports healthy blood circulation and normal fibrinolytic activity.
For Athletes: High-potency nattokinase (providing 12,000 Fibrinolytic Units) supports healthy blood flow and circulation. Athletes concerned with cardiovascular health may benefit from nattokinase’s ability to help maintain normal blood viscosity and support the body’s natural
clot-dissolving mechanisms. Nattokinase also may help maintain normal vascular function during intense training periods, supporting optimal nutrient delivery to working muscles and maintaining circulatory health.
Why We Chose These Ingredients
Blood pressure management during anabolic use isn’t optional – it’s mission-critical. Most athletes can’t feel elevated blood pressure, making it a silent threat to performance and longevity. Our triple-action approach targets this issue from multiple angles:
Arjuna delivers cardioprotection through antioxidant activity while directly improving cardiac performance: “an increase in left ventricular stroke volume index, and an increase in LVEF were recorded suggesting improvement. On long-term evaluation (20-28 months), in addition to continued improvement in symptoms and signs, they also reported an improvement in quality of life.”
Hawthorn Berry Extract acts as a powerful vasorelaxant, reducing peripheral resistance while increasing coronary blood flow: “Vasorelaxant effects on vascular smooth muscles previously artificially contracted by catecholamines were noted by Vierling et al. who postulated that this could have significant clinical importance as raised catecholamine levels are present in the bloodstream during heart failure.”
Nattokinase attacks the problem at its source – arterial plaque: “A significant reduction in the thickness of the carotid artery intima-media and the size of the carotid plaque was observed. The improvement rates ranged from 66.5 to 95.4%.”
This strategic combination supports healthy blood pressure through multiple mechanisms: vasorelaxation, increased stroke volume, and reduced arterial plaque – creating comprehensive support for athletes pushing physiological boundaries.
Arjuna: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220499/
Hawthorn Berry: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249900/
Overall Heart Function
Vitamin K2 2600mcg
Claim:
“Supports bone health and may reduce artery calcification”
Evidence: https://pmc.ncbi.nlm.nih.gov/articles/PMC7238900/#ref1
Summary:
The above link is an analysis of many studies that show Vitamin K2 helping prevent calcification of the arteries. Some more recent studies have shown that K2 may not reverse disease so it’s best to be looked at as a preventative measure. Arteries aside, K2 is well proved to aid in distributing calcium in the body to bones, preventing osteoporosis and improving bone health and strength.
Coenzyme Q10:
Claim:
“Supports Heart Health”
Evidence:
Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem – PMC (nih.gov)
Summary:
Co Q10 is a compound found in the mitochondria and is a key component for the movement of electrons through cells and ATP production. Supplementing CoQ10 would function similar to creatine but be used in the circulatory system. “Besides the functions of COQ10 mentioned before, one of the actions of COQ10 in HF is the inotropic one. It improves cardiac output by the rise of heart’s contractile force [60]. It is supposed that COQ10 improves the oxygen utilization on the cellular level.” Studies show improvement of blood presure with patients who are hypertensive but no change with patients that have normal blood pressure. ”when the blood pressure is normal, administration of COQ10 didn’t modify the blood pressure [33–35]. In other words, the antihypertensive effect of COQ10 is limited only to patients with hypertension and does not decrease systemic pressure in patients without hypertension.”
May interact with blood pressure medications. Consult your doctor before using.
Why We Chose These Ingredients
While most ingredients in ORBITAL DEFENSE target specific systems, CoQ10 and Vitamin K2 provide foundational cellular support throughout the body. Our research revealed a powerful synergistic effect between Nattokinase and K2, creating enhanced cardiovascular protection beyond what either could provide alone.
CoQ10 production naturally declines after age 30, precisely when many athletes are reaching their peak performance years. For athletes operating at extreme levels of physical output, cellular energy production and antioxidant protection become non-negotiable requirements.
ORBITAL DEFENSE wasn’t designed for average athletes taking basic supplements. It was engineered for those pushing beyond natural limits who require comprehensive protection at the cellular level. These ingredients provide that synergistic foundation.
K2: https://pmc.ncbi.nlm.nih.gov/articles/PMC7238900/#ref1
CoQ10: Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem – PMC (nih.gov)
*Required FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.